Home > Products > albumin & IL-6R > Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv4-Ig)

Recombinant Human Anti-albumin x Human Anti-IL-6R Bispecific Antibody (scFv4-Ig)  (FVTIG-H194)

Recombinant Anti-albumin x Anti-IL-6R Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-albumin scFv is fused to the CH1 domain of a heavy chain and another anti-IL-6R scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can act as PK-modulated receptor antagonist. It is designed for the research of Lupus, rheumatoid arthritis therapy.

Specifications
Targets
albumin & IL-6R
Type
Appended IgGs
Species Reactivity
Human
Target 1
albumin
Host Animal 1
Human
Target 2
IL-6R
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Systemic lupus erythematosus (SLE); Rheumatoid arthritis (RA)
Targets
Target 1
albumin
Gene ID
UniProt ID
Alternative Names
ALB; albumin; HAS; PRO0883; PRO0903; PRO1341
Target 2
IL-6R
Gene ID
UniProt ID
Alternative Names
IL6R; IL-6R; interleukin 6 receptor; IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1
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