Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (Fab-IgG) (FABIG-007)

Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can act as PK-modulated ligand antagonist. It is designed for the research of Lupus and rheumatoid arthritis therapy.

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Specifications

Targets

albumin & TNF

Type

Fab-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Systemic lupus erythematosus (SLE); Rheumatoid arthritis (RA)

Targets

Target 1

albumin

Gene ID

213

UniProt ID

P02768

Alternative Names

ALB; albumin; HAS; PRO0883; PRO0903; PRO1341

Target 2

TNF

Gene ID

7124

UniProt ID

P01375

Alternative Names

TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNFα; cachectin; APC1 protein; TNF, monocyte-derived; TNF-α; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (Fab-IgG) (CAT#: FABIG-007)

Specifications

Targets

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