Home > Products > Ang2 & VEGFA > Recombinant Anti-Ang2 x Anti-VEGFA Bispecific Antibody (Tandem Diabody)

Recombinant Anti-Ang2 x Anti-VEGFA Bispecific Antibody (Tandem Diabody)  (CAT#: T-BSDB-008)

Recombinant Anti-Ang2 x Anti-VEGFA Bispecific Antibody (Tandem Diabody) is designed to be expressed as a monomeric subunit (single chain Diabody, scDb), with four variable domains from two parental antibodies. Then the two peptide chains can dimerize in a head-to-tail fashion. This BsAb is capable of inhibiting two proangiogenics fators and a combined blockade of them has a greater inhibitory efficacy compared with inhibition of either factor alone. It is designed for the research of Colorectal cancer (CRC); Solid tumors; Wet AMD (Age-related macular degeneration); Diabetic macular edema therapy.
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Specifications

Targets
Ang2 & VEGFA
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Colorectal cancer (CRC); Solid tumors; Wet AMD (Age-related macular degeneration); Diabetic macular edema

Targets

Target 1
Ang2
Gene ID
UniProt ID
Alternative Names
ANGPT2; Ang2; angiopoietin 2; ANG2; AGPT2; angiopoietin-2; ANG-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a
Target 2
VEGFA
Gene ID
UniProt ID
Alternative Names
VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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