Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Diabody-Fc) (BSDBF-012)

Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-AR and anti-DNA antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can enter prostate cancer cells and inhibits androgen receptor function. It is designed for the research of prostate cancer therapy.

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Specifications

Targets

AR & DNA

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Prostate cancer

Targets

Target 1

Gene ID

367

UniProt ID

P10275

Alternative Names

AR; androgen receptor; KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; dihydrotestosterone receptor; androgen nuclear receptor variant 2; nuclear receptor subfamily 3 group C member 4

Target 2

DNA

Alternative Names

DNA; Deoxyribonucleic acid

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Diabody-Fc) (CAT#: BSDBF-012)

Specifications

Targets

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