Home > Products > AR & DNA > Recombinant Anti-AR x Anti-DNA Bispecific Antibody (F(ab')2-scFv2)

Recombinant Anti-AR x Anti-DNA Bispecific Antibody (F(ab')2-scFv2)  (BABFV-012)

Recombinant Anti-AR x Anti-DNA Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-AR specificity is fused to the C terminus of the anti-DNA Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can enter prostate cancer cells and inhibits androgen receptor function. It is designed for the research of prostate cancer therapy.

Specifications

Targets
AR & DNA
Type
Fab-Fc Fusion Proteins
Species Reactivity
Human
Target 1
AR
Host Animal 1
Mouse
Target 2
DNA
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Prostate cancer

Targets

Target 1
AR
Gene ID
UniProt ID
Alternative Names
AR; androgen receptor; KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; dihydrotestosterone receptor; androgen nuclear receptor variant 2; nuclear receptor subfamily 3 group C member 4
Target 2
DNA
Alternative Names
DNA; Deoxyribonucleic acid

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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