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Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scFv-CH3)  (CAT#: BSFC-012)

Recombinant Anti-AR x Anti-DNA Bispecific Antibody (scFv-CH3) contains two chains. The anti-AR scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-DNA scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can enter prostate cancer cells and inhibits androgen receptor function. It is designed for the research of prostate cancer therapy.
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Specifications

Targets
AR & DNA
Type
scFv-CH3
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Prostate cancer

Targets

Target 1
AR
Gene ID
UniProt ID
Alternative Names
AR; androgen receptor; KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; dihydrotestosterone receptor; androgen nuclear receptor variant 2; nuclear receptor subfamily 3 group C member 4
Target 2
DNA
Alternative Names
DNA; Deoxyribonucleic acid
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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