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Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Triple Body)  (TRIB-012)

Recombinant Anti-AR x Anti-DNA Bispecific Antibody (Triple Body) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from an anti-AR antibody are both extended with the scFv fragment from an anti-DNA antibody. This BsAb can enter prostate cancer cells and inhibits androgen receptor function. It is designed for the research of prostate cancer therapy.

Specifications

Targets
AR & DNA
Type
Triple Body
Species Reactivity
Human
Target 1
AR
Host Animal 1
Mouse
Target 2
DNA
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Prostate cancer

Targets

Target 1
AR
Gene ID
UniProt ID
Alternative Names
AR; androgen receptor; KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; dihydrotestosterone receptor; androgen nuclear receptor variant 2; nuclear receptor subfamily 3 group C member 4
Target 2
DNA
Alternative Names
DNA; Deoxyribonucleic acid

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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