Name: Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc)
SKU: FABVC-015
Rating: 5 (1 reviews)

Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-B cell lymphoma A20-HL Idiotype antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-CD3 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.

Datasheet INQUIRY

Specifications

Targets

B cell lymphoma A20-HL Idiotype & CD3

Type

Fab-scFv/sdAb-Fc

Species Reactivity

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

B cell lymphoma

Host Animal 1

Rat

Host Animal 2

Mouse

Targets

Target 1

B cell lymphoma A20-HL Idiotype

Alternative Names

B cell lymphoma A20-HL Idiotype; B cell lymphoma; A20-HL; Idiotype; Id

Target 2

CD3

Gene ID

12501

UniProt ID

P24161

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3; AI504783

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-015)

Specifications

Targets

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