Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-B cell lymphoma A20-HL Idiotype and anti-CD3 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.
Specifications
Targets
B cell lymphoma A20-HL Idiotype & CD3
Type
Constant Domain-extended Bispecific Fragments
Target 1
B cell lymphoma A20-HL Idiotype
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma
Targets
Target 1
B cell lymphoma A20-HL Idiotype
Alternative Names
B cell lymphoma A20-HL Idiotype; B cell lymphoma; A20-HL; Idiotype; Id
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3; AI504783
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