Home > Products > B cell lymphoma A20-HL Idiotype & CD3 > Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (scFv-Fc-scFv)

Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (scFv-Fc-scFv)  (BSTF-015)

Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-B cell lymphoma A20-HL Idiotype scFv is fused to the N-terminus of Fc via a hinge region while another anti-CD3 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.

Specifications
Targets
B cell lymphoma A20-HL Idiotype & CD3
Type
scFv-Fc-scFv
Species Reactivity
Mouse
Target 1
B cell lymphoma A20-HL Idiotype
Host Animal 1
Rat
Target 2
CD3
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma
Targets
Target 1
B cell lymphoma A20-HL Idiotype
Alternative Names
B cell lymphoma A20-HL Idiotype; B cell lymphoma; A20-HL ; Idiotype; Id
Target 2
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3; AI504783
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