Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (scFv-Fc-scFv) (BSTF-015)

Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-B cell lymphoma A20-HL Idiotype scFv is fused to the N-terminus of Fc via a hinge region while another anti-CD3 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.

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Specifications

Targets

B cell lymphoma A20-HL Idiotype & CD3

Type

scFv-Fc-scFv

Species Reactivity

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

B cell lymphoma

Targets

Target 1

B cell lymphoma A20-HL Idiotype

Alternative Names

B cell lymphoma A20-HL Idiotype; B cell lymphoma; A20-HL ; Idiotype; Id

Target 2

CD3

Gene ID

12501

UniProt ID

P24161

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3; AI504783

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-015)

Specifications

Targets

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