Recombinant Anti-B cell lymphoma BCL1 Idiotype x Anti-CD3 Bispecific Antibody (Minibody) (MiniB-016)

Recombinant Anti-B cell lymphoma BCL1 Idiotype x Anti-CD3 Bispecific Antibody (Minibody) is designed to be expressed as the anti-B cell lymphoma BCL1 Idiotype scFv fused to N-terminus of Knob-CH3 domain and the anti-CD3 scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.

Datasheet

Specifications

Targets

B cell lymphoma BCL1 Idiotype & CD3

Type

Minibody

Species Reactivity

Mouse

Target 1

B cell lymphoma BCL1 Idiotype

Host Animal 1

Rat

Target 2

CD3

Host Animal 2

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

B cell lymphoma

Targets

Target 1

B cell lymphoma BCL1 Idiotype

Alternative Names

B cell lymphoma BCL1 Idiotype; B cell lymphoma; BCL1; Idiotype; Id; 31D1; 32D1

Target 2

CD3

Gene ID

12501

UniProt ID

P24161

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3; AI504783

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