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Recombinant Anti-B cell lymphoma BCL1 Idiotype x Anti-CD64 Bispecific Antibody (Fab-IgG)  (CAT#: FABIG-001)

Recombinant Anti-B cell lymphoma BCL1 Idiotype x Anti-CD64 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can retarget immune cells to tumor cells. It is designed for the research of B cell lymphoma therapy.
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Specifications

Targets
B cell lymphoma BCL1 Idiotype & CD64
Type
Fab-IgG
Species Reactivity
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma

Targets

Target 1
B cell lymphoma BCL1 Idiotype
Alternative Names
B cell lymphoma BCL1 Idiotype; B cell lymphoma; BCL1; Idiotype; Id; 31D1; 32D1
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FcγRI; FCGR1A; Fc fragment of IgG, high affinity Ia, receptor (CD64); CD64; FCRI; CD64A; IGFR1; high affinity immunoglobulin gamma Fc receptor I; fcgammaRIa; Fc-gamma RI; fc-gamma RIA; Fc gamma receptor; IgG Fc receptor I; Fc-gamma receptor I A1; Fc fragment of IgG, high affinity Ia, receptor for (CD64); FCGR1B, FCGR1C
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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