Recombinant Anti-B cell lymphoma BCL1 Idiotype x Anti-CD64 Bispecific Antibody (scFv-CH3) contains two chains. The anti-B cell lymphoma BCL1 Idiotype scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-CD64 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can retarget immune cells to tumor cells. It is designed for the research of B cell lymphoma therapy.
Specifications
Targets
B cell lymphoma BCL1 Idiotype & CD64
Type
scFv-based Bispecific Fragments
Target 1
B cell lymphoma BCL1 Idiotype
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma
Targets
Target 1
B cell lymphoma BCL1 Idiotype
Alternative Names
B cell lymphoma BCL1 Idiotype; B cell lymphoma; BCL1; Idiotype; Id; 31D1; 32D1
Alternative Names
FcγRI; FCGR1A; Fc fragment of IgG, high affinity Ia, receptor (CD64); CD64; FCRI; CD64A; IGFR1; high affinity immunoglobulin gamma Fc receptor I; fcgammaRIa; Fc-gamma RI; fc-gamma RIA; Fc gamma receptor; IgG Fc receptor I; Fc-gamma receptor I A1; Fc fragment of IgG, high affinity Ia, receptor for (CD64); FCGR1B, FCGR1C
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