Home > Products > B7H6 & CD3 > Recombinant Anti-B7H6 x Anti-CD3 Bispecific Antibody (Tandem Fab)

Recombinant Anti-B7H6 x Anti-CD3 Bispecific Antibody (Tandem Fab)  (BSFAB-017)

Recombinant Anti-B7H6 x Anti-CD3 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-B7H6 and anti-CD3 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget T cells to tumor cells. It is designed for the research of Hematologic neoplasms; Solid tumors therapy.

Specifications
Targets
B7H6 & CD3
Type
Tandem Fab
Species Reactivity
Human
Target 1
B7H6
Host Animal 1
Mouse
Target 2
CD3
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Hematologic neoplasms; Solid tumors
Targets
Target 1
B7H6
Gene ID
UniProt ID
Alternative Names
NCR3LG1; natural killer cell cytotoxicity receptor 3 ligand 1; B7H6; B7-H6; DKFZp686O24166; natural cytotoxicity triggering receptor 3 ligand 1; B7 homolog 6; putative Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167
Target 2
CD3
Gene ID
UniProt ID
Alternative Names
C3AR1; complement C3a receptor 1; AZ3B; C3AR; HNFAG09; CR3; Complement receptor type 3; CD11b/CD18; Mac-1; Macrophage antigen 1; αmβ2

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