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Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-019)
Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scFv-CH3) contains two chains. The anti-BAFF scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-IL17 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can neutralize both BAFF and IL- 17 simultaneously. It is designed for the research of Lupus Nephritis (LN); Systemic Lupus Erythematosus (SLE); Rheumatoid Arthritis (RA); Psoriasis (Ps); Ankylosing Spondylitis (AS); Psoriatic Arthritis (PA) primary Sjögren's Syndrome (pSS); Multiple Myeloma (MM) therapy.
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