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Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scFv-IgG) (CAT#: BSSG-019)
Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-BAFF antibody variable domain are respectively connected to the N terminus of the anti-IL17 IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can neutralize both BAFF and IL- 17 simultaneously. It is designed for the research of Lupus Nephritis (LN); Systemic Lupus Erythematosus (SLE); Rheumatoid Arthritis (RA); Psoriasis (Ps); Ankylosing Spondylitis (AS); Psoriatic Arthritis (PA) primary Sjögren's Syndrome (pSS); Multiple Myeloma (MM) therapy.
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