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Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scFv4-Ig) (CAT#: FVTIG-019)
Recombinant Anti-BAFF x Anti-IL17 Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-BAFF scFv is fused to the CH1 domain of a heavy chain and another anti-IL17 scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can neutralize both BAFF and IL- 17 simultaneously. It is designed for the research of Lupus Nephritis (LN); Systemic Lupus Erythematosus (SLE); Rheumatoid Arthritis (RA); Psoriasis (Ps); Ankylosing Spondylitis (AS); Psoriatic Arthritis (PA) primary Sjögren's Syndrome (pSS); Multiple Myeloma (MM) therapy.
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