Recombinant Human Anti-BCMA x Human Anti-CD3 Bispecific Antibody (IgG(L)-scFv) (IGLFV-H200)

Recombinant Anti-BCMA x Anti-CD3 Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-BCMA antibody are fused to the C terminus of an anti-CD3 IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can retarget T cells to tumor cells. It is designed for the research of Multiple myeloma (MM) therapy.

Datasheet INQUIRY

Specifications

Targets

BCMA & CD3

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple myeloma (MM)

Targets

Target 1

BCMA

Gene ID

608

UniProt ID

Q02223

Alternative Names

TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein

Target 2

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-BCMA x Human Anti-CD3 Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-H200)

Specifications

Targets

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