Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-BCMA specificity is fused to the C terminus of the anti-TACI Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can bind two receptors simultaneously. It is designed for the research of Lymphoma therapy.
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