Home > Products > BCMA & TACI > Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Fv-IgG)

Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (Fv-IgG)  (BSDG-H201)

Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-BCMA IgG with similar domains from an anti-TACI antibody via short peptide linkers, or vice versa. This BsAb can bind two receptors simultaneously. It is designed for the research of Lymphoma therapy.

Specifications

Targets
BCMA & TACI
Type
Appended IgGs
Species Reactivity
Human
Target 1
BCMA
Host Animal 1
Human
Target 2
TACI
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Lymphoma

Targets

Target 1
BCMA
Gene ID
UniProt ID
Alternative Names
TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein
Target 2
TACI
Gene ID
UniProt ID
Alternative Names
TNFRSF13B; tumor necrosis factor receptor superfamily, member 13B; CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor 13B; transmembrane activator and CAML interactor

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