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Recombinant Human Anti-BCMA x Human Anti-TACI Bispecific Antibody (scDiabody-Fc)  (CAT#: SCDBF-H201)

Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scDiabody-Fc) is a fusion protein of two scDiabodies with an Fc region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-BCMA/anti-TACI diabody. The scDiabody with two specificities is further fused to the Fc domain to form BsAb with 2+2 antigen-binding valency. This BsAb can bind two receptors simultaneously. It is designed for the research of Lymphoma therapy.
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Specifications

Targets
BCMA & TACI
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Lymphoma

Targets

Target 1
BCMA
Gene ID
UniProt ID
Alternative Names
TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein
Target 2
TACI
Gene ID
UniProt ID
Alternative Names
TNFRSF13B; tumor necrosis factor receptor superfamily, member 13B; CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor 13B; transmembrane activator and CAML interactor
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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