Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scFv-Fc) (BSCFV-021)

Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-BCMA specificity or anti-TACI specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can bind two receptors simultaneously. It is designed for the research of Lymphoma therapy.

Datasheet INQUIRY

Specifications

Targets

BCMA & TACI

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Lymphoma

Targets

Target 1

BCMA

Gene ID

608

UniProt ID

Q02223

Alternative Names

TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein

Target 2

TACI

Gene ID

23495

UniProt ID

O14836

Alternative Names

TNFRSF13B; tumor necrosis factor receptor superfamily, member 13B; CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor 13B; transmembrane activator and CAML interactor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (scFv-Fc) (CAT#: BSCFV-021)

Specifications

Targets

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