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Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Single-chain Diabody)  (SCDB-021)

Recombinant Anti-BCMA x Anti-TACI Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can bind two receptors simultaneously. It is designed for the research of Lymphoma therapy.

Specifications

Targets
BCMA & TACI
Type
Single-chain Diabody
Species Reactivity
Human
Target 1
BCMA
Host Animal 1
Mouse
Target 2
TACI
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Lymphoma

Targets

Target 1
BCMA
Gene ID
UniProt ID
Alternative Names
TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein
Target 2
TACI
Gene ID
UniProt ID
Alternative Names
TNFRSF13B; tumor necrosis factor receptor superfamily, member 13B; CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor 13B; transmembrane activator and CAML interactor

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