Home > Products > C. albicans & CD64 > Recombinant Anti-C. albicans x Anti-CD64 Bispecific Antibody (scFv-CH1/CL)

Recombinant Anti-C. albicans x Anti-CD64 Bispecific Antibody (scFv-CH1/CL)  (BSCC-023)

Recombinant Anti-C. albicans x Anti-CD64 Bispecific Antibody (scFv-CH1/CL) is designed to be expressed as two chains. One scFv from an anti-C. albicans antibody variable domain is fused to CH1 and the other scFv from an anti-CD64 antibody variable domain fused to CL, or vice versa. And the CH1 and CL domains are linked covalently via a natural disulfide bond. This BsAb can retarget of neutrophils to Candida albicans. It is designed for the research of Candida albicans infection therapy.

Specifications

Targets
C. albicans & CD64
Type
scFv-CH1/CL
Species Reactivity
Human
Target 1
C. albicans
Host Animal 1
Mouse
Target 2
CD64
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Candida albicans infection

Targets

Target 1
C. albicans
Alternative Names
C. albicans; Candida albicans; Debaryomycetaceae; Candida
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

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