Recombinant Anti-C. albicans x Anti-CD64 Bispecific Antibody (scFv-Fc-scFv) (BSTF-023)

Recombinant Anti-C. albicans x Anti-CD64 Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-C. albicans scFv is fused to the N-terminus of Fc via a hinge region while another anti-CD64 scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can retarget of neutrophils to Candida albicans. It is designed for the research of Candida albicans infection therapy.

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Specifications

Targets

C. albicans & CD64

Type

scFv-Fc-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Candida albicans infection

Targets

Target 1

C. albicans

Alternative Names

C. albicans; Candida albicans; Debaryomycetaceae; Candida

Target 2

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-C. albicans x Anti-CD64 Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-023)

Specifications

Targets

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