Recombinant Anti-CA72-4 x Anti-CD3 Bispecific Antibody (F(ab')2-scFv2)  (BABFV-027)

Recombinant Anti-CA72-4 x Anti-CD3 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-CA72-4 specificity is fused to the C terminus of the anti-CD3 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can retarget T cells to tumor cells. It is designed for the research of Gastrointestinal cancer; Ovarian cancer; Colon cancer; Gastric cancer; Breast cancer; Adenocarcinomas therapy.

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