Home > Products > CA72-4 & CD3 > Recombinant Human Anti-CA72-4 x Human Anti-CD3 Bispecific Antibody (scFv-CH3)

Recombinant Human Anti-CA72-4 x Human Anti-CD3 Bispecific Antibody (scFv-CH3)  (CAT#: BSFC-H204)

Recombinant Anti-CA72-4 x Anti-CD3 Bispecific Antibody (scFv-CH3) contains two chains. The anti-CA72-4 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-CD3 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can retarget T cells to tumor cells. It is designed for the research of Gastrointestinal cancer; Ovarian cancer; Colon cancer; Gastric cancer; Breast cancer; Adenocarcinomas therapy.
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Specifications

Targets
CA72-4 & CD3
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Gastrointestinal cancer; Ovarian cancer; Colon cancer; Gastric cancer; Breast cancer; Adenocarcinomas

Targets

Target 1
CA72-4
Alternative Names
CA72-4; Cancer antigen 72-4; Carbohydrate antigen 72-4
Target 2
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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