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Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (Bibody) (CAT#: BIBD-028)
Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (Bibody) is a Fab-scFv format that uses heterodimeric Fab as a scaffold, and a scFv region linked to one of its heavy (Fd) or light (L) chain. The scFv of the anti-CCR3 specificity is fused to the anti-CCR3 heavy or light chain of the Fab. This BsAb canreduce eosinophil signaling, inhibit bronchoalveolar lavage fluid inflammation, eosinophil, mast cell mediator release and reverse lung inflammation. It is designed for the research of Asthma therapy.
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