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Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (IgG-Fv) (CAT#: BSGV-028)
Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-CCR3 antibody variable domain is fused to the C terminal of an IgG of anti-CD300 antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb canreduce eosinophil signaling, inhibit bronchoalveolar lavage fluid inflammation, eosinophil, mast cell mediator release and reverse lung inflammation. It is designed for the research of Asthma therapy.
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