Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (Minibody)  (MiniB-028)

Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (Minibody) is designed to be expressed as the anti-CCR3 scFv fused to N-terminus of Knob-CH3 domain and the anti-CD300 scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb canreduce eosinophil signaling, inhibit bronchoalveolar lavage fluid inflammation, eosinophil, mast cell mediator release and reverse lung inflammation. It is designed for the research of Asthma therapy.

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