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Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (Tandem Diabody)  (CAT#: T-BSDB-028)

Recombinant Anti-CCR3 x Anti-CD300 Bispecific Antibody (Tandem Diabody) is designed to be expressed as a monomeric subunit (single chain Diabody, scDb), with four variable domains from two parental antibodies. Then the two peptide chains can dimerize in a head-to-tail fashion. This BsAb canreduce eosinophil signaling, inhibit bronchoalveolar lavage fluid inflammation, eosinophil, mast cell mediator release and reverse lung inflammation. It is designed for the research of Asthma therapy.
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Specifications

Targets
CCR3 & CD300
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Asthma

Targets

Target 1
CCR3
Gene ID
UniProt ID
Alternative Names
CCR3; C-C motif chemokine receptor 3; CKR3; CD193; CMKBR3; CC-CKR-3
Target 2
CD300
Gene ID
UniProt ID
Alternative Names
CD300A; CD300a molecule; IRC1; IRC2; CLM-8; IRp60; IGSF12; CMRF35H; CMRF-35H; CMRF35-H; CMRF35H9; CMRF35-H9; IRC1/IRC2; CMRF-35-H9
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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