Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (F(ab')2-scFv2)  (BABFV-029)

Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-CCR5 specificity is fused to the C terminus of the anti-CD3 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can retarget T cells to CCR5 target cells. It is designed for the research of HIV-1 infection, AIDS therapy.

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