Home > Products > CCR5 & CD3
> Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc)
Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-029)
Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-CCR5 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-CD3 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget T cells to CCR5 target cells. It is designed for the research of HIV-1 infection, AIDS therapy.
There are currently no customer reviews or questions for Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (Fab-scFv-Fc) (FABVC-029). Click the button below to contact us or submit your feedback about this product.