Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (Tandem scFv-Fc)  (BSFVF-029)

Recombinant Anti-CCR5 x Anti-CD3 Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-CCR5/CD3 tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb can retarget T cells to CCR5 target cells. It is designed for the research of HIV-1 infection, AIDS therapy.

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