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Recombinant Anti-CD123 x Anti-CD3 Bispecific Antibody (Fv-IgG) (CAT#: BSDG-030)
Recombinant Anti-CD123 x Anti-CD3 Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-CD123 IgG with similar domains from an anti-CD3 antibody via short peptide linkers, or vice versa. This BsAb can retarget T cells to tumor cells. It is designed for the research of Acute myelogenous leukemia (AML); Chronic myelogenous leukemia (CML); Plasmacytoid leukemia therapy.
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