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Recombinant Anti-CD123 x Anti-CD3 Bispecific Antibody (scFv-IgG) (CAT#: BSSG-030)
Recombinant Anti-CD123 x Anti-CD3 Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD123 antibody variable domain are respectively connected to the N terminus of the anti-CD3 IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the research of Acute myelogenous leukemia (AML); Chronic myelogenous leukemia (CML); Plasmacytoid leukemia therapy.
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