Name: Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (F(ab')2-scFv2)
SKU: BABFV-032
Rating: 5 (1 reviews)

Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-CD15 specificity is fused to the C terminus of the anti-CD64 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can retarget neutrophils to tumor cells. It is designed for the research of Leukemia therapy.

Datasheet INQUIRY

Specifications

Targets

CD15 & CD64

Type

F(ab')2-scFv2

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Leukemia

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD15

Gene ID

2526

UniProt ID

P22083

Alternative Names

FUT4; fucosyltransferase 4; LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; 3-FAL; 3-fucosyl-N-acetyllactosamine; stage-specific embryonic antigen-1; Lewis X; X-hapten

Target 2

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (F(ab')2-scFv2) (BABFV-032). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-032)

Specifications

Targets

Customer Reviews and Q&As