Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (Fv-IgG) (BSDG-032)

Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (Fv-IgG) is an appended IgG format, which has 2+2 antigen-binding valency. This dual variable domain IgG is generated by appending variable domains of an anti-CD15 IgG with similar domains from an anti-CD64 antibody via short peptide linkers, or vice versa. This BsAb can retarget neutrophils to tumor cells. It is designed for the research of Leukemia therapy.

Datasheet INQUIRY

Specifications

Targets

CD15 & CD64

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Leukemia

Targets

Target 1

CD15

Gene ID

2526

UniProt ID

P22083

Alternative Names

FUT4; fucosyltransferase 4; LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; 3-FAL; 3-fucosyl-N-acetyllactosamine; stage-specific embryonic antigen-1; Lewis X; X-hapten

Target 2

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (Fv-IgG) (CAT#: BSDG-032)

Specifications

Targets

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