Home > Products > CD15 & CD64 > Recombinant Human Anti-CD15 x Human Anti-CD64 Bispecific Antibody (IgG-Fv)

Recombinant Human Anti-CD15 x Human Anti-CD64 Bispecific Antibody (IgG-Fv)  (BSGV-H209)

Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-CD15 antibody variable domain is fused to the C terminal of an IgG of anti-CD64 antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb can retarget neutrophils to tumor cells. It is designed for the research of Leukemia therapy.

Specifications

Targets
CD15 & CD64
Type
IgG-Fv
Species Reactivity
Human
Target 1
CD15
Host Animal 1
Mouse
Target 2
CD64
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Leukemia

Targets

Target 1
CD15
Gene ID
UniProt ID
Alternative Names
FUT4; fucosyltransferase 4; LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; 3-FAL; 3-fucosyl-N-acetyllactosamine; stage-specific embryonic antigen-1; Lewis X; X-hapten
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

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