Home > Products > CD15 & CD64 > Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (Miniantibody)

Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (Miniantibody)  (MNAB-032)

Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-CD15 antibody variable domain is linked to another scFv of an anti-CD64 antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can retarget neutrophils to tumor cells. It is designed for the research of Leukemia therapy.

Specifications
Targets
CD15 & CD64
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CD15
Host Animal 1
Mouse
Target 2
CD64
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Leukemia
Targets
Target 1
CD15
Gene ID
UniProt ID
Alternative Names
FUT4; fucosyltransferase 4; LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; 3-FAL; 3-fucosyl-N-acetyllactosamine; stage-specific embryonic antigen-1; Lewis X; X-hapten
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Our services and products are only for lab research, not for any diagnostic or therapeutic use.

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