Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (Single-chain Diabody) (SCDB-032)

Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can retarget neutrophils to tumor cells. It is designed for the research of Leukemia therapy.

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Specifications

Targets

CD15 & CD64

Type

Single-chain Diabody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Leukemia

Targets

Target 1

CD15

Gene ID

2526

UniProt ID

P22083

Alternative Names

FUT4; fucosyltransferase 4; LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; 3-FAL; 3-fucosyl-N-acetyllactosamine; stage-specific embryonic antigen-1; Lewis X; X-hapten

Target 2

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD15 x Anti-CD64 Bispecific Antibody (Single-chain Diabody) (CAT#: SCDB-032)

Specifications

Targets

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