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Recombinant Human Anti-CD15 x Anti-DENV Bispecific Antibody (Fab-IgG)  (FABIG-H208)

Recombinant Anti-CD15 x Anti-DENV Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb is designed for the research of antibody-dependent enhancement (ADE) and dengue virus infection.

Specifications

Targets
CD15 & DENV
Type
Fab-IgG
Species Reactivity
Human
Target 1
CD15
Host Animal 1
Human
Target 2
DENV
Host Animal 2
Human
Application
FuncS
Related Disease
Dengue virus infection

Targets

Target 1
CD15
Gene ID
UniProt ID
Alternative Names
FUT4; fucosyltransferase 4; LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; 3-FAL; 3-fucosyl-N-acetyllactosamine; stage-specific embryonic antigen-1; Lewis X; X-hapten
Target 2
DENV
Alternative Names
dengue virus; DENV; dengue fever; Flavivirus

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