Home > Products > CD15 & DENV > Recombinant Anti-CD15 x Anti-DENV Bispecific Antibody (scFv4-Ig)

Recombinant Anti-CD15 x Anti-DENV Bispecific Antibody (scFv4-Ig)  (FVTIG-033)

Recombinant Anti-CD15 x Anti-DENV Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-CD15 scFv is fused to the CH1 domain of a heavy chain and another anti-DENV scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb is designed for the research of antibody-dependent enhancement (ADE) and dengue virus infection.

Specifications
Targets
CD15 & DENV
Type
Appended IgGs
Species Reactivity
Human
Target 1
CD15
Host Animal 1
Mouse
Target 2
DENV
Host Animal 2
Mouse
Application
FuncS
Related Disease
Dengue virus infection
Targets
Target 1
CD15
Gene ID
UniProt ID
Alternative Names
FUT4; fucosyltransferase 4; LeX; CD15; ELFT; FCT3A; FUTIV; SSEA-1; FUC-TIV; 3-FAL; 3-fucosyl-N-acetyllactosamine; stage-specific embryonic antigen-1; Lewis X; X-hapten
Target 2
DENV
Alternative Names
dengue virus; DENV; dengue fever; Flavivirus
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