Home > Products > CD16 & CD30 > Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-Fv)

Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-Fv)  (FABFV-034)

Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-CD16 antibody are fused with the VL and VH domains of an anti-CD30 antibody respectively. It can form natural in vivo heterodimerization. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL) therapy.

Specifications
Targets
CD16 & CD30
Type
Fab-Fv
Species Reactivity
Human
Target 1
CD16
Host Animal 1
Mouse
Target 2
CD30
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL)
Targets
Target 1
CD16
Gene ID
UniProt ID
Alternative Names
FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA; low affinity immunoglobulin gamma Fc region receptor III-A; FcγRIII; FcgammaRIIIA; CD16a antigen; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; igG Fc receptor III-2; Fc gamma receptor III-A; Fc-gamma receptor IIIb (CD16); neutrophil-specific antigen NA; Fc-gamma receptor III-2 (CD 16); immunoglobulin G Fc receptor III; Fc fragment of IgG, low affinity III, receptor for (CD16)
Target 2
CD30
Gene ID
UniProt ID
Alternative Names
TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30
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