Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-CD16 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-CD30 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL) therapy.
There are currently no customer reviews or questions for Recombinant Anti-CD16 x Anti-CD30 Bispecific Antibody (Fab-scFv-Fc) (FABVC-034). Click the button below to contact us or submit your feedback about this product.
Welcome! For price inquiries, we will get back to you as soon as possible.
INQUIRYSERVICES
PRODUCTS
PLATFORMS