Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-CD16 antibody variable domain is fused to the C terminal of an IgG of anti-CD32B antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb is capable of cross-linking of FcγR to activate neutrophils and mediating cellular responses. It is designed for the research of Solid tumors therapy.
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