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Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (scFv-CH3) (CAT#: BSFC-035)
Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD16 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-CD32B scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb is capable of cross-linking of FcγR to activate neutrophils and mediating cellular responses. It is designed for the research of Solid tumors therapy.
FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); FcγRIIB; CD32; FCG2; CD32B; FCGR2; IGFR2; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32)
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