Home > Products > CD16 & CD32B > Recombinant Human Anti-CD16 x Human Anti-CD32B Bispecific Antibody (scFv-Fc)

Recombinant Human Anti-CD16 x Human Anti-CD32B Bispecific Antibody (scFv-Fc)  (BSCFV-H212)

Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-CD16 specificity or anti-CD32B specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb is capable of cross-linking of FcγR to activate neutrophils and mediating cellular responses. It is designed for the research of Solid tumors therapy.

Specifications
Targets
CD16 & CD32B
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CD16
Host Animal 1
Mouse
Target 2
CD32B
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors
Targets
Target 1
CD16
Gene ID
UniProt ID
Alternative Names
FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA; low affinity immunoglobulin gamma Fc region receptor III-A; FcγRIII; FcgammaRIIIA; CD16a antigen; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; igG Fc receptor III-2; Fc gamma receptor III-A; Fc-gamma receptor IIIb (CD16); neutrophil-specific antigen NA; Fc-gamma receptor III-2 (CD 16); immunoglobulin G Fc receptor III; Fc fragment of IgG, low affinity III, receptor for (CD16)
Target 2
CD32B
Gene ID
UniProt ID
Alternative Names
FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); FcγRIIB; CD32; FCG2; CD32B; FCGR2; IGFR2; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32)
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