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Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (scFv-IgG) (CAT#: BSSG-035)
Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD16 antibody variable domain are respectively connected to the N terminus of the anti-CD32B IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb is capable of cross-linking of FcγR to activate neutrophils and mediating cellular responses. It is designed for the research of Solid tumors therapy.
FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); FcγRIIB; CD32; FCG2; CD32B; FCGR2; IGFR2; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32)
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