Recombinant Anti-CD16 x Anti-CD32B Bispecific Antibody (Tandem scFv-Fc) is designed to be expressed as a homodimer, which has 2+2 antigen-binding valency. This format consists of one Fc region and two tandem scFv fragments, in which the anti-CD16/CD32B tandem scFv is fused to the Fc domain. The engineered fragment format is used to extend the half-life. This BsAb is capable of cross-linking of FcγR to activate neutrophils and mediating cellular responses. It is designed for the research of Solid tumors therapy.
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